Tomasz Maj简介

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Tomasz Maj

研究员,博士生导师

immunology, tumor immunology, autoimmunity, immune tolerance

个人概述 / 科研方向 / 招生要求

      I am a professor at the institute of Molecular Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine. My research interests concentrate on the mechanisms of immune tolerance、immunosuppression、and autoimmunity. I have published more than 20 papers in academic journals such as Cell, Nature Immunology, Science Immunology and Cancer Immunology. We welcome everybody with background in biochemistry, molecular biology, cell biology, immunology or related field to discuss potential collaboration or become a new lab member.

教育背景

1999.10–2002.06 University of Wrocław, Institute of Genetics and Microbiology, biology with a specialization of microbiology,BSc

2002.10–2004.06 University of Wrocław, Institute of Genetics and Microbiology, biology with a specialization in Microbiology, MSc

2004.09–2011.12 Institute of Immunology and Experimental Therapy, Wrocław, Biological Sciences, PhD

 

工作经历

2012.04–2016.02 University of Michigan, Department of Surgery, Medical School, post-doctoral training in immunology/cancer immunology.

2016.03–2019.10 University of Michigan, Department of Surgery, Medical School, research specialist senior.

2019.11-present Renji Hospital, Shanghai Jiao Tong University School of Medicine, Institute of Molecular Medicine, Professor.

代表性文章 / 专利
  1. Maj T, Wang W, Crespo J, Zhang H, Wang W, Wei S, Zhao L, Vatan L, Shao I, Szeliga W, Lyssiotis C, Liu RJ, Kryczek I, Zou W. Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor. Nat Immunol 2017; 18:1332.
  2. Zhao E, Maj T, Kryczek I, Li W, Wu K, Zhao L, Wei S, Crespo J, Wan S, Vatan L, Szeliga W, Shao I, Wang Y, Liu Y, Varambally S, Chinnaiyan AM, Welling TH, Marquez V, Kotarski J, Wang H, Wang Z, Zhang Y, Liu R, Wang G, Zou W. Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction. Nat Immunol 2016; 17:95-103.
  3. Wang W, Kryczek I, Dostal L, Lin H, Tan L, Zhao L, Lu F, Wei S, Maj T, Peng D, He G, Vatan L, Szeliga W, Kuick R, Kotarski J, Tarkowski R, Dou Y, Rattan R, Munkarah A, Liu JR, Zou W. Effector T cells abrogate stroma-mediated chemoresistance in ovarian cancer. Cell 2016; 165:1-14.