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张鹏
上海交通大学医学院分子医学研究院研究员,博士生导师
pengzhang016@sjtu.edu.cn
外泌体液体活检和靶向治疗
个人概述 / 科研方向 / 招生要求
上海交通大学医学院分子医学研究院研究员,博士生导师。入选国家高层次青年人才计划,上海市海外高层次人才计划,上海市“东方学者”特聘教授,曾获美国K-INBRE博士后奖。研究兴趣主要包括新型微流控分析平台、智能分子识别器件、功能化微囊泡靶向治疗等,研究成果发表在Nature Biomedical Engineering,Science Translational Medicine等顶尖杂志。欢迎对临床检验诊断、生物医用材料、分子医学以及分析化学感兴趣的才俊加入。
教育背景
2014年9月至2019年9月 堪萨斯大学化学系分析化学(美国) 博士后
2009年9月至2014年7月 复旦大学化学系分析化学 硕博连读
2005年9月至2009年5月 复旦大学化学系应用化学 本科
工作经历
2019年9月至今 上海交通大学医学院分子医学研究院 研究员
代表性文章 / 专利
文章
- BQ Lin, YM Lei, JX Wang, L Zhu, YQ Wu, HM Zhang, LL Wu, P Zhang*, CY Yang*, Microfluidic-based exosome analysis for liquid biopsy, Small Methods, 2021, 2001131
- P Zhang, XQ Wu, GH Gardashova, YH Zhang, Y Yang, L Xu*, Y Zeng*, Integrative molecular and functional exosome analysis to monitor tumor progression and metastasis using inkjet-printed 3D-nanopatterned microchips. Science Translational Medicine., 2020, 12, eaaz2878.
- P Zhang, X Zhou, M He, YQ Shang, AL Tetlow, AK Godwin, Y Zeng*, Ultrasensitive detection of circulating exosomes with a 3D-nanopatterned microfluidic chip. Nature Biomedical Engineering, 2019, 3, 438-451.
- P Zhang, X Zhou, Y Zeng*, Multiplexed immunophenotying of circulating exosomes on nano-engineered ExoProfile chip towards early diagnosis of cancer. Chemical Science, 2019, 10, 5495-5504.
- P Zhang, J Crow, D Lella, X Zhou, G Samuel, AK Godwin*, Y Zeng*, Ultrasensitive quantification of tumor mRNAs in extracellular vesicles with an integrated microfluidic digital analysis chip. Lab on a chip, 2018, 18, 3790-3801.
- P Zhang, M He, Y Zeng*, Ultrasensitive microfluidic analysis of circulating exosomes using a nanostructured graphene oxide/poly dopamine coating. Lab on a chip, 2016, 16, 3033-3042.
- P Zhang, R Zhang, MX Gao*, X. M Zhang*, Novel nitrocellulose membrane substrate for efficient analysis of circulating tumor cells coupled with surface-enhanced raman scattering imaging. ACS Applied Materials & Interfaces. 2014, 6, 370−376.
- P Zhang, G Samuel, J Crow, AK Godwin*, Y Zeng*, Molecular assessment of circulating exosomes towards liquid biopsy diagnosis of Ewing sarcoma family of tumors. Translational Research, 2018, 201, 136-153.
- P Zhang, XN Fang, GQ Yan, MX Gao,* XM Zhang*, Highly efficient enrichment of low-abundance intact proteins by core-shell structured Fe3O4-chitosan@graphene composites. Talanta, 2017, 174,845-852.
- P Zhang, M. X Gao*, S. C Zhu, J Lei, X. M. Zhang*, Rapid and efficient proteolysis through laser-assisted immobilized enzyme reactors. J. Chromatogr. A. 2011, 1218, 8567-8571.
- P Zhang, CL Sun, R Zhang, MX Gao*, X. M Zhang*, A novel and facile microchip based on nitrocellulose membrane toward efficient capture of circulating tumor cells. Chinese Journal of Chromatography. 2013, 31, 518−521.
专利
- 高明霞、张祥民、张鹏 发明专利“一种基于硝酸纤维素膜的便捷细胞捕获芯片” 专利申请号201310139673.0
- 高明霞、张祥民、张鹏、洪广峰 发明专利“一种原位聚合蛋白质快速酶解整体柱的制备方法及其应用” 专利号ZL200910047016.7